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steeljack 27-05-2008 05:39

anyone taken part in a 'new' drug trial
 
My cardiologist who I have full confidence in (but who's probably getting a kickback) asked if I was interested in taking part in a 'new' heart medication blind trial (wont be told if I'm on the stuff or a placebo), did one a few years back for a 'new' super heart drug (got a phone call at work to stop taking it with immediate effect ).
How do other Accy-web users feel about being used as human guinea pigs ? , personally I have no objection , if it works , good , if it doesnt ...oh well , sure the stuff has been well tested on rats and chimps, with no serious side effects , and probably in some third world country and now they want to test the stuff on folks with "western/European" lifestyles.
I just have a problem with the drug companies whilst doing noble works in finding new cures and stuff, have some of their priorities screwed up , they make Billions with a B on stuff like Viagra ,yet expect folks to volunteer (unpaid) for medications which in my mind are more important .
What do you think , should human guniea pigs recieve some recompense from the drug companies or not ? , note, volunteering for partaking in a trial means signing reams and reams of paperwork absolving the manufacturer of any responsibility .
p.s. I'm not a skinflint looking for money , just the fact that these Drug companies profits are outrageous to my way of thinking .

Anyone care to comment .......


also why don't new paragraph indents work ?

Mick 27-05-2008 06:05

Re: anyone taken part in a 'new' drug trial
 
2 Attachment(s)
What was the Drug you where testing?
i did one with the new all singing all dancing stents these are to open the arteries up the new ones are coated in slow release drugs anti coagulant and blood thinning drugs they where testing i got 3 of them at a cost of £2000 each and i am still here

Mancie 27-05-2008 07:03

Re: anyone taken part in a 'new' drug trial
 
I was in a bad state around 3yrs ago..2 persons came to my bed and told me they had a new drug that may or may not save me.. they said they would try it out on 3 patients, one by jab, one by mouth and one by drip, I told them I would be happy to take the drug but only by drip..they mumbled and grumbled but I took it by drip but still don't know the outcome.. no one told me, but to be honest I would have taken anything.
I did hear from a doc that there is a new drug that gets you off warfarin.. but don't know the facts

Mick 27-05-2008 07:08

Re: anyone taken part in a 'new' drug trial
 
i think the one your on about mancie is "clopidogrel"(plavix) i am on it

cashman 27-05-2008 08:56

Re: anyone taken part in a 'new' drug trial
 
not being a killjoy steeljack, but was a bad case of this approx 2 yrs back over here, some of the trialists were in a real bad way, (someone may remember) i would think long n hard if yer a fit person, the up side - ya will be able to afford yer Tina concert.:D;)

jaysay 27-05-2008 09:10

Re: anyone taken part in a 'new' drug trial
 
I was once the first person to be put on an asthma drug in this area some years ago, was on it about two years but didn't do much good, I've even forgotten the name, but it was in a yellow and brown inhaler:confused:

cashman 27-05-2008 09:12

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by jaysay (Post 582224)
I was once the first person to be put on an asthma drug in this area some years ago, was on it about two years but didn't do much good, I've even forgotten the name, but it was in a yellow and brown inhaler:confused:

if i was suffering in anyway i would be the first to try em, but fit,would think long n hard.;)

garinda 27-05-2008 09:23

Re: anyone taken part in a 'new' drug trial
 
Being a YOP, someone who was diagnosed with Parkinson's Disease under forty, hence Young Onset Parkinson's, is quite rare, and I'm often asked to trial new drugs.

I really don't mind, in the hope it could help me as well as research.

Some of the side effects have been horrendous, hallucinations, hearing voices, projectile vomiting. Pretty much what happens after a good night at an Accy Web meet.:D

I recently trialed a new drug patch. Again I had to stop when the side effects became too bad, though I did make them laugh when my biggest complaint was that it was just too fiddly for people with Parkinson's, as it involved opening too tiny foil envelopes, and peeling back the plaster, a bit hard to do when your fingers don't do what you want them to do.:D

MargaretR 27-05-2008 09:45

Re: anyone taken part in a 'new' drug trial
 
I get paracetemol for pain and Zantak for acid reflux - neither have side effects, and can be bought 'over the counter'

Any fancier drugs I have been given have had side effects and so I can't take them.

Some people are more prone to get side effects than others, and when I see the potential for damage to other internal organs from prescription drugs, in some ways I am thankful that I can survive without them.

When I tell my doc that paracetemol doesn't relieve pain, he says 'try whisky'.
When I tell him I spend half my life asleep, he says 'drink lots of coffee'.

I just try to improve my quality of life using herbal remedies. They don't come free on NHS, but I know that they won't kill me off, (if taken in recommended dosages)

jaysay 27-05-2008 10:55

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by [email protected] (Post 582239)
I get paracetemol for pain and Zantak for acid reflux - neither have side effects, and can be bought 'over the counter'

Any fancier drugs I have been given have had side effects and so I can't take them.

Some people are more prone to get side effects than others, and when I see the potential for damage to other internal organs from prescription drugs, in some ways I am thankful that I can survive without them.

When I tell my doc that paracetemol doesn't relieve pain, he says 'try whisky'.
When I tell him I spend half my life asleep, he says 'drink lots of coffee'.

I just try to improve my quality of life using herbal remedies. They don't come free on NHS, but I know that they won't kill me off, (if taken in recommended dosages)

Its the only problem taking drugs for any illness, there are side effects, I was talking to my specialist last week and asked him about a drug I take for Oseoporosis called fosamax, which give some people irregular heart beat, he just said my heartbeat was fine and not to worry, mind you I only have osteoporosis through taking steriods in the first place, and take df118s for the pain, which are also very strong, I also take losec because of stomach problems caused by mediction, it just one big visious circle, but if you want to live thats the price you have pay

jambutty 27-05-2008 13:43

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by steeljack (Post 582195)
My cardiologist who I have full confidence in (but who's probably getting a kickback) asked if I was interested in taking part in a 'new' heart medication blind trial (wont be told if I'm on the stuff or a placebo), did one a few years back for a 'new' super heart drug (got a phone call at work to stop taking it with immediate effect ).
How do other Accy-web users feel about being used as human guinea pigs ? , personally I have no objection , if it works , good , if it doesnt ...oh well , sure the stuff has been well tested on rats and chimps, with no serious side effects , and probably in some third world country and now they want to test the stuff on folks with "western/European" lifestyles.
I just have a problem with the drug companies whilst doing noble works in finding new cures and stuff, have some of their priorities screwed up , they make Billions with a B on stuff like Viagra ,yet expect folks to volunteer (unpaid) for medications which in my mind are more important .
What do you think , should human guniea pigs recieve some recompense from the drug companies or not ? , note, volunteering for partaking in a trial means signing reams and reams of paperwork absolving the manufacturer of any responsibility .
p.s. I'm not a skinflint looking for money , just the fact that these Drug companies profits are outrageous to my way of thinking .

Anyone care to comment .......


also why don't new paragraph indents work ?

The only problem with taking part in drug trials is that you have to stop taking your normal medication, which hopefully has been keeping you hale and hearty.

What if the ‘new’ drug isn’t as effective as your old one? Or worse still doesn’t do anything and you get very ill or even snuff it?

Apart from all that, if the drug companies want to trial a new drug on humans they should pay them AND if the trial goes wrong, fork out substantial pre-determined damages.

AccyLass 27-05-2008 14:13

Re: anyone taken part in a 'new' drug trial
 
No I would never do any trial like this, I am quite lucky really and don't use any medication

It is obviously good for research, but I would not want to put myself forward for this

Bonnyboy 27-05-2008 14:15

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by cashman (Post 582220)
not being a killjoy steeljack, but was a bad case of this approx 2 yrs back over here, some of the trialists were in a real bad way, (someone may remember) i would think long n hard if yer a fit person, the up side - ya will be able to afford yer Tina concert.:D;)

Think this is the story you mean cashy - BBC News

Six blokes ended up in intensive care within hours of taking the drug. Two were critically ill, think one bloke in particular was at deaths door.

I’m sure I read that there is a participation fee of around £150 - £200 per day, cant find any info on this, so I could well be wrong.

pam1 27-05-2008 14:23

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by Bonnyboy (Post 582334)
Think this is the story you mean cashy - BBC News

Six blokes ended up in intensive care within hours of taking the drug. Two were critically ill, think one bloke in particular was at deaths door.

I’m sure I read that there is a participation fee of around £150 - £200 per day, cant find any info on this, so I could well be wrong.

bonnyboy you got it in one

AccyLass 27-05-2008 14:23

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by Bonnyboy (Post 582334)
Think this is the story you mean cashy - BBC News

Six blokes ended up in intensive care within hours of taking the drug. Two were critically ill, think one bloke in particular was at deaths door.

I’m sure I read that there is a participation fee of around £150 - £200 per day, cant find any info on this, so I could well be wrong.


The last bit on your comment doesn't sound so good when ya can't spend it:p

cashman 27-05-2008 14:24

Re: anyone taken part in a 'new' drug trial
 
thats the one bonnyboy, odds on riskin yer health if fit, i aint prepared to take.

BERNADETTE 27-05-2008 14:29

Re: anyone taken part in a 'new' drug trial
 
I suppose if the drugs could benefit you in the future then you might consider testing them. I have been lucky not to have been in that position but can imagine if I was and all the other drugs weren't helping then trying a new drug would be ok. At the end of the day these drugs have to be taken by someone to see if they work. The decision ultimately is down to you if you are prepared to be one of the first to try them.

Bonnyboy 27-05-2008 14:34

Re: anyone taken part in a 'new' drug trial
 
Well it’s certainly something you don’t want to entertain for the sake of some extra cash.

accyman 27-05-2008 21:37

Re: anyone taken part in a 'new' drug trial
 
was it last year or the year before when 7 people or so nearly died when their heads blew up to 4x their origional size when doing these drug trials lol

may sound like easy money but you take a risk when you do it

however

a bloke i worked with did a weeks drug trial somwhere and they had to stay in the hospital while they were doing the trials

he got paid a couple of grand and also CLAIMED to have slept with a couple of the nurses

guess its up to you what you think the pros and cons are lol

Lilly 27-05-2008 22:08

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by Bonnyboy (Post 582334)
Think this is the story you mean cashy - BBC News

Six blokes ended up in intensive care within hours of taking the drug. Two were critically ill, think one bloke in particular was at deaths door.

I’m sure I read that there is a participation fee of around £150 - £200 per day, cant find any info on this, so I could well be wrong.

I remember that.

I saw the photo in the paper of the fella who's head blew up to something like 4 times its size......he looked like the elephant man and he was due to get married soon. That was why he did the trial, to help with the cost.

I think drug trials are a marvellous thing but stories like these don't half put you off.

Bonnyboy 27-05-2008 22:16

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by Lilly (Post 582557)
I remember that.

I saw the photo in the paper of the fella who's head blew up to something like 4 times its size......he looked like the elephant man and he was due to get married soon. That was why he did the trial, to help with the cost.

I think drug trials are a marvellous thing but stories like these don't half put you off.

I'm not at all sure that cash incentives for participants in clinical trials are completely ethical.

jaysay 28-05-2008 09:39

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by Bonnyboy (Post 582576)
I'm not at all sure that cash incentives for participants in clinical trials are completely ethical.

The only trouble is that without clinical trials a drug won't be licenced, you may get people who will try out new lotions and portions because it may help their condition, but in some cases that isn't always possible

Loz 28-05-2008 12:01

Re: anyone taken part in a 'new' drug trial
 
There is no way i would take part in a drugs trial!
I can't even take paracetemol without side effects,i think it would be hazardous for me!

Bonnyboy 28-05-2008 12:33

Re: anyone taken part in a 'new' drug trial
 
Quote:

Originally Posted by jaysay (Post 582717)
The only trouble is that without clinical trials a drug won't be licenced, you may get people who will try out new lotions and portions because it may help their condition, but in some cases that isn't always possible

Appreciate what you are saying jaysay. The Companies have to do the trials as you point out. I just don’t think the situation is ideal , giving cash incentives to increase participant rate.

It’s hardly ideal, it’s easy for folk like myself to criticise the situation. Much harder to come up with an alternative.


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