Make sure you have plenty of time available and don't let young children near your PS2 whilst playing. I had GTA San Andreas shipped over to me here in Germany. I played it for approximately two hours before my daughter decided to yank the PS2 onto the floor and destroy the CD-Draw and disk within!
There is a lot to be said for the XBox and it's child proof controller ports.....
By the way, is GTA-SA coming out for the XBox? I wont be getting it for the PS2 again, that is for sure!