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This from the BBC might be interesting...

Car exhausts contain a range of toxic substances that can have a serious impact on health. Once released into the air, these substances are breathed in and transported in the bloodstream to all the body's major organs.
Potentially dangerous vehicle emissions include:

• Carbon monoxide
• Nitrogen dioxide
• Sulphur dioxide
• Benzene
• Formaldehyde
• Polycyclic hydrocarbons
• Lead
• Tiny suspended particles

It is estimated that air pollution - of which vehicle emissions are the major contributor - is responsible for 24,000 premature deaths in the UK every year. Many of these deaths are due to asthma, bronchitis and other respiratory diseases - all of which are known to be aggravated by exposure to car fumes.

A Dutch study, published in March, of 632 children aged 7 to 11 years found that respiratory disorders worsened as air pollution increased.

Impact on blood

Many pollutants produce harmful effects on the blood and the coronary system. Researchers estimate that one in every 50 heart attacks in London are triggered by air pollution.

Lead, for instance, interferes with the normal formation of red blood cells by inhibiting important enzymes. It also damaged red blood cell membrances and interferes with cell metabolism in a way that shortens the survival of each individual cell. This can lead to anaemia - a shortage of blood cells - which can reduce the body's ability to circulate oxygen and vital nutrients.

Benzene has a suppressive effect on bone marrow and impairs the development of red blood cells. Exposure to the chemical may result in a diminished number of blood cells - cytopenia - or total bone marrow loss.

Carbon monoxide (CO) poisoning is similar to suffocation. CO binds to the haemoglobin contained in red blood cells 200 times more effectively than oxygen, and so can dramatically reduce the ability of the cells to transport and release oxygen to the tissues of the body.

Toxic chemicals may also stimulate the immune system to attack the body's own tissues, particularly the cells that line human blood vessels.

The damage is initially slight, but it can build up with repetitive exposure to toxic substances and eventually lead to blockage of the blood vessels, increasing the risk of high blood pressure and heart disease.

Central nervous system

Research has shown that exposure to lead can lead to behavioural changes. It can also impair mental function, causing problems with learning and memory.

German research suggests that the impact of lead on the central nervous system may grow with advancing age. The immune system appears to be particularly vulnerable to the effects of pollution.

Substances such as benzene, nitrogen dioxide and small particulate matter interact with the immune system and may cause changes, ranging from overactive immune responses to immunosuppression.

Cause of cancer

Long-term exposure to Benzene has been shown to be linked to leukaemia. It is also thought that the harmful impact that the chemical can have on the immune system may lower the body's defence against tumours. Polycyclic hydrocarbons are also thought to be carcinogenic.

Several of these compounds have caused tumours in laboratory animals when they ate them, when they were applied to their skin, or when they breathed them in the air for long periods of time. Studies in animals have also shown that polycyclic hydrocarbons can cause harmful effects on the skin and on body fluids.

(Source: BBC News)