The above answers make an assumption that you can re-point your browser to to the page of your choice using the menu options in the browser.
Whilst this is a possibility for a simple hijack, this will never work in the more malicious and persistant browser hijacks. The comment "have tried to fix with Ad-Aware, Spybot, McAfee etc - still no good " is the clue here.
The more malicious hijacks are very good at putting things back the way they were. So simple fixes will not work.
So how do you solve your problem ?
Well I am not going to tell you, as I do not know your skill level.
If I had a brain tumour I wouldn't let you near me, even if you had some skill with a knife and a turkey.<grin>
What I will do, is point you in a direction so you can understand the problem first, and then you can decide whether you feel comfortable to proceed.
Here is the low down on your problem.
Proceed with caution....
http://www.pcstats.com/articleview.cfm?articleID=1579